HOW TO ADMINISTER
BUCCOLAM (Midazolam)

How to administer BUCCOLAM (Midazolam)

Please review the information leaflet on how to administer BUCCOLAM which can be downloaded here.

Please advise your patients and carers to read the patient information leaflet inside the box for additional signs indicating need for medical support.

Before administering BUCCOLAM:

  • Ensure the patient is not in any physical danger, remove glasses and loosen tight clothing.
  • Support the patient’s head with something soft, such as a cushion or your lap.
  • Follow the advice of your healthcare professional or follow the Patient Care Plan.
Administering Buccolam -1

1

Remove the syringe from the tube.

2

Remove the red cap and dispose of safely. Please ensure that the inner translucent tip cap has also been fully removed. If necessary, it must be manually removed BEFORE administration, to ensure it does not fall into the patient’s mouth.

3

Gently hold the cheek away from the teeth.

4

Insert the tip of the syringe between the lower gum and cheek.

5

Slowly release the solution by gently pressing the plunger until empty. If prescribed by your doctor (for larger volumes and/or smaller patients), you can give approximately half the dose slowly into one side of the mouth, then into the other side of the child’s mouth.

6

Note the time that Buccolam was administered. Stay with the patient until they are fully recovered.

7

Retain empty syringe for the ambulance or healthcare professional.

Call An Ambulance Immediately If:

  • The seizure does not stop within 10 minutes of administering BUCCOLAM
  • You cannot administer BUCCOLAM, or cannot give the full dose
  • The patient’s breathing slows down or stops
  • The patient vomits and the seizure does not stop within 10 minutes of administering BUCCOLAM
  • You observe signs of a heart attack such as chest pain or pain that
    spreads to the neck or shoulders and down the left arm
  • You give too much BUCCOLAM and there are signs of overdose (see patient information leaflet)

Never Give Another Dose of BUCCOLAM:

  • Even if the seizure does not stop within 10 minutes
  • If the patient vomits or salivates

Please read the patient information leaflet inside the box for additional signs indicating need for medical support.

Administration Demonstration

The following video can be used for training both HCPs and patients/carers. It demonstrates how to administer BUCCOLAM
during a seizure.
This video is also available for patients and carers.

Play Video

For infants aged 3-6 months, treatment should be in a hospital setting where monitoring is possible and resuscitation equipment is available.

References:

This information is provided as a resource to HCP’s who prescribe or administer Buccolam.

Reporting of adverse events (Healthcare Professionals in the UK)

Adverse events should be reported. Reporting forms and information can be found at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. Adverse events should also be reported to Neuraxpharm. at: pv-uk@neuraxpharm.com